The hotel has welcomed travelers since 1885, when Florence was a stop on the Grand Tour. Writers, artists, and performers became part of its history, with actress Eleonora Duse making it her long-term Florentine residence. The historic Helvetia wing retains antiques and artworks alongside Italian fabrics and glass. Bristol occupies the former Banco di Roma premises, where Anouska Hempel interprets the interiors of Florentine palaces through a contemporary arrangement of space and light. The two wings share a commitment to craft, but their rooms have different decorative identities.
Herringbone oak floors, damask fabrics, Murano glass lighting, and marble give the interiors much of their texture. The hotel's collection includes paintings, mirrors, Chinese vases, and antique seating, with pietra serena stone from Fiesole lining the lobby and corridors. Florentine workshops have contributed textiles and lighting as well as furniture. These are details encountered throughout the house, not confined to a single showpiece suite. Upholstered seating and framed art continue through the public areas, maintaining the furnished character of a residence.