The Masseria San Domenico lies about eight hundred meters from the sea on the coast between Bari and Brindisi. It is one of the oldest watchtowers built in the XIV century. This fortified building was used to warn against attacks by the Turks. After a careful restoration, completed respecting the old shapes and the original building materials, the tower was converted into a deluxe resort whose charm recalls the region's history, a land where the Eastern and the Mediterranean cultures have mixed well together. Against the backdrop of the blue sky and sea, the whitewashed stone buildings stand out amidst ancient silver olive groves, among which there lies a magnificent irregularly-shaped pool encircled by rocks and plants.

The hotel has 30 double rooms and 16 suites. Every room has a quite similar decor to each other, with marble floors, crisp white walls, cheerful floral drapes and matching bedspreads in different colors for every room, stenciled designs accenting the ceilings, and fanciful painted wrought-iron headboards. Every room is provided with a minibar, satellite TV, direct-dial telephone, access to the Internet, safe box, air-conditioning, and hairdryer. Some of the rooms capture the blue of the Adriatic Sea across an expanse of olive trees.

The hotel's main restaurant, the San Domenico Restaurant, with its arched vaults dating back to the 1700s, is renowned both locally and internationally for its exquisite food. The restaurant offers Apulian specialties complemented by a selection of fine local wines. Guests can have breakfast in Sala Fico while the Pool Grill serves a daily regional buffet lunch. Recently opened, the seafood restaurant "La Nassa" located in the "a mare" dependence promises an unforgettable eating experience savoring the local fish and seafood delicacies.

As well as the outdoor swimming pool, the hotel has 2 private beaches (one sandy, one rocky), two tennis courts, a sauna and a steam bath, and an 18-hole golf course overlooking the sea. Masseria San Domenico is home to one of Italy's best thalassotherapy spas. The spa offers various treatments and uses the rich seawater and seaweed found in the nearby Adriatic Sea, just 500 meters away.